ABSTRACT
Pulmonary hypertension (PH) is a severe disease that can progress to clinical decompensation, risk of hospitalization and death owing to disease-related or other diseases. In the context of coronavirus disease 2019 (COVID-19), PH was considered a risk factor for complications. The purpose of the study was to assess the mortality rate of COVID-19 in PH patients from a PH Center in Brazil. We conducted a telephone survey between June and August 2021 among all patients or relatives from the PH referral center who were followed after the first case of COVID- 19 in Brazil. Only patients with a confirmed diagnosis of PH were included in the analysis. Of the 426 patients followed in the first 18 months of the pandemic, 115 patients were excluded (lost to follow-up, post-acute PE or unconfirmed PH). Among 311 patients included, 39 had a confirmed diagnosis of COVID-19 (COVID-19 + ), and 38.5% of patients were hospitalized. The estimated incidence rate was 12.5%. Comparing the COVID-19+ versus patients without infection (COVID-19 - ) in the period, the mean age was similar (55 +/- 17 vs. 54 +/- 16 years) and the majority in the COVID-19+ group were female (85% vs. 69%, p = 0.039), respectively. There was no difference in the proportion of patients diagnosed with pulmonary arterial hypertension (PAH;49% and 42%) and chronic thromboembolic pulmonary hypertension (CTEPH;24% and 33%) between groups. All PAH patients and the majority of CTEPH patients were treated on specific therapy (combination/triple therapy, 70%). The case fatality rate in the PH-COVID-19+ group was 23%. Considering only PAH and CTEPH, the case fatality rate was 21,9%, while COVID-19 mortality was 2.9% and overall lethality in Brazil was 2.8%. In the COVID-19+ group, the mean pulmonary artery pressure was 48 +/- 14 mmHg, cardiac index 2.7 +/- 0.6 L/min/m2 and pulmonary vascular resistance 730 +/- 424 dyn.s/cm5. In conclusion, among PH patients there was high incidence and mortality from COVID-19, even in those with PHspecific therapy. Further studies are needed to evaluate the prognostic predictors in PH-COVID-19 patients.
ABSTRACT
Pulmonary hypertension (PH) is a severe disease that can progress to clinical decompensation, risk of hospitalization and death owing to disease-related or other diseases. In the context of coronavirus disease 2019 (COVID-19), PH was considered a risk factor for complications. The purpose of the study was to assess the mortality rate of COVID-19 in PH patients from a PH Center in Brazil. We conducted a telephone survey between June and August 2021 among all patients or relatives from the PH referral center who were followed after the first case of COVID- 19 in Brazil. Only patients with a confirmed diagnosis of PH were included in the analysis. Of the 426 patients followed in the first 18 months of the pandemic, 115 patients were excluded (lost to follow-up, post-acute PE or unconfirmed PH). Among 311 patients included, 39 had a confirmed diagnosis of COVID-19 (COVID-19 + ), and 38.5% of patients were hospitalized. The estimated incidence rate was 12.5%. Comparing the COVID-19+ versus patients without infection (COVID-19 - ) in the period, the mean age was similar (55 +/- 17 vs. 54 +/- 16 years) and the majority in the COVID-19+ group were female (85% vs. 69%, p = 0.039), respectively. There was no difference in the proportion of patients diagnosed with pulmonary arterial hypertension (PAH;49% and 42%) and chronic thromboembolic pulmonary hypertension (CTEPH;24% and 33%) between groups. All PAH patients and the majority of CTEPH patients were treated on specific therapy (combination/triple therapy, 70%). The case fatality rate in the PH-COVID-19+ group was 23%. Considering only PAH and CTEPH, the case fatality rate was 21,9%, while COVID-19 mortality was 2.9% and overall lethality in Brazil was 2.8%. In the COVID-19+ group, the mean pulmonary artery pressure was 48 +/- 14 mmHg, cardiac index 2.7 +/- 0.6 L/min/m2 and pulmonary vascular resistance 730 +/- 424 dyn.s/cm5. In conclusion, among PH patients there was high incidence and mortality from COVID-19, even in those with PHspecific therapy. Further studies are needed to evaluate the prognostic predictors in PH-COVID-19 patients.
ABSTRACT
The word 'sejahtera' or in English known as well-being or prosperity is widely used in Nusantara as a fundamental concept of human existence which is usually applied to various dimensions of life: physical, spiritual, intellectual, emotional, economic, political, governance, educational, social, cultural and religious. Furthermore, the Malay concept of 'sejahtera' has received wide attention from our community during this pandemic COVID19 to ensure communities health. It is an important concept that deals with the issue of quality of life, society and civilisation as well. Given its importance, nurturing, and sustaining of a humane, peaceful, balanced and prosperous civilisation in this period of heightened global crises, in which most of mankind are currently starving for 'sejahtera' and struggling against an unprecedented COVID-19 pandemic, the Malay concept of 'sejahtera' will be reviewed from an Islamic thought perspective to build an alternative paradigm of holistic and sustainable development from the worldview of Tawhid. The study found that the Malaysian government's MySejahtera programme, which uses a digital platform to serve as a one-stop shop, can help in a way to prevent the spread of COVID-19 in line with national law in achieving Maqasid al-Shari'ah.
ABSTRACT
This article reviews energy management schemes for smart homes integrated with renewable energy resources in the context of the COVID-19 pandemic. The incorporation of distributed renewable energy system has initiated an acute transition from the traditional centralized energy management system to independent demand responsive energy systems. Renewable energy-based Smart Home Energy Management Systems (SHEMSs) play a vital role in the residential sector with the increased and dynamic electricity demand during the COVID-19 pandemic to enhance the efficacy, sustainability, economical benefits, and energy conservation for a distribution system. In this regard, the reviews of various energy management schemes for smart homes appliances and associated challenges has been presented. Different energy scheduling controller techniques have also been analyzed and compared in the COVID-19 framework by reviewing several cases from the literature. The utilization and benefits of renewable-based SHEMS have also been discussed. In addition, both micro and macro-level socio-economic implications of COVID-19 on SHEMSs are discussed. A conclusion has been drawn given the strengths and limitations of different energy scheduling controllers and optimization techniques in the context of the COVID-19 pandemic. It is observed that renewable-energy-based SHEMS with improved multi-objective meta-heuristic optimization algorithms employing artificial intelligence are better suited to deal with the dynamic residential energy demand in the pandemic. It is hoped that this review, as a fundamental platform, will facilitate the researchers aiming to investigate the performance of energy management and demand response schemes for further improvement, especially during the pandemic.
ABSTRACT
The spread of fake news on COVID-19 is causing public unrest and suspicion among citizens which is a challenge for countries facing the pandemic. The misinformation or disinformation which stems from uncertainties, unrest, and anxiety because of movement control order procedures, financial and economic hardship caused wrong information to spread like fire. Often referred to as 'info-demic', it becomes a second source of virulent information that requires arresting just like the pandemic itself. Controlling fake news in a pandemic is a daunting problem that slaps Internet regulation on its face. On the Internet, lies spread faster than the truth, and correcting this misinformation is a tonne of work. In this paper, we examine Internet self- and coregulatory approaches in selected jurisdictions to reduce the impact of fake news on governments, industry, and private actors. Through a qualitative method and doctrinal content analysis, this article examines the various approaches adopted in arresting fake news. In the first section, we analysed specific legislation enacted by parliaments that criminalised the acts of disseminating and publishing fake news. In the second section, we found efforts to impose civil and criminal liability on platform providers to monitor online content. In the final section, we analysed self- and co-regulatory efforts to introduce online fact-checking portals and awareness campaigns. This research argues that the Internet self-regulation system in Malaysia is not bringing the desired result i.e., maintaining peace and security of the nation. Considering the impact of dangerous misinformation on society, more so in a global emergency like the present COVID-19 pandemic, it is submitted that co-regulation is more suitable if the social, moral, and cultural fabric of the society is to be maintained.
ABSTRACT
The spread of fake news on Covid19 is causing public unrest and suspicion among citizens which is a challenge for countries facing the pandemic. The misinformation or disinformation which stems from uncertainties, unrest, and anxiety because of movement control order procedures, financial and economic hardship caused wrong information to spread like fire. Called as 'info-demic', it becomes a second source of virulent information that requires arresting just like the pandemic itself. Controlling fake news in the time of pandemic is a daunting problem that slaps Internet regulation at its face. On the Internet, lies spreads faster than truth and correcting misinformation means tonnes of work. This paper examines Internet self- and co-regulatory approaches in selected jurisdictions to reduce the impact of fake news on governments, industry, and private actors. In applying content analysis as a qualitative research method, the first section analysed specific legislations enacted by parliaments to criminalise the acts of disseminating and publishing fake news. The second section examines legislative and administrative efforts to impose civil and criminal liability on platform providers to monitor online content. The final section analysed self-regulatory efforts to introduce online fact-checking portals and awareness campaigns. This paper argues that Internet self-regulation scheme in Malaysia is not bringing the desired result in the scope of maintaining peace and security of the nation. Considering how dangerous disinformation can cause to the society, more so in global emergency like the present Covid19 pandemic, it is submitted that Internet co-regulation is more suitable if the social, moral and cultural fabric of the society is to be maintained. © 2021 Universiti Putra Malaysia. All rights reserved.